Plant & Animal Genome IX Conference

Computer: Demonstrations
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MULTIQTL, AN INTERACTIVE PACKAGE FOR GENETIC MAPPING OF CORRELATED QUANTITATIVE TRAIT COMPLEXES IN MULTIPLE ENVIRONMENTS, VERSION 2.0 (DEMO)

Institute of Evolution, University of Haifa, Mount Carmel, Haifa, 31905, Israel

We are developing a multipurpose user-friendly QTL mapping package for plants and animals that includes a broad spectrum of options for: (i) analysis and interpretation of real data; (ii) optimization of ongoing experiments (including computer-assisted sequential mapping and tools for fine mapping); and (iii) designing of new experiments. The package proved to be an efficient platform for teaching (at undergraduate and graduate levels). The new version of MultiQTL includes tools for data transformation, data mining, multiple trait analysis (up to 15 traits could be treated simultaneously in the DEMO version 2.0), testing genotype-environmental interactions, using selective genotyping for single and multiple trait analysis, fitting co-segregating QTLs as co-factors; analysis of linked QTLs and testing various hypotheses about intralocus allele interactions and epistasis, discriminating between linkage and pleiotropy, etc. Permutation tests, bootstrapping and Monte-Carlo simulations are used to estimate the significance, test power and confidence intervals of the parameter estimates. More information on the software can be found at: http://www.MultiQTL.com