Plant & Animal Genomes XIV Conference Plant & Animal Genomes XIV ConferenceJanuary 14-18, 2006
Town & Country Convention Center
San Diego, CA
Zhi-liang Hu , Max F. Rothschild , James Reecy
Rapid developments in animal genomics have resulted in an overwhelming amount of information from divergent areas of research, which need to be integrated, linked, and analyzed. While it remains a challenge to build a “complete genomics data pipeline” for everything, our efforts to extend the functionality of the Pig QTL Database (PigQTLdb) represent a useful approach. First, we have added a set of curator/editor tools to PigQTLdb, in which a number of restrictions and checkpoints are enforced during the curation process for data integrity, consistency, and error checks. Second, we have added an animal trait ontology editing tool (ATO editor) to build and manage the ontology of traits. Third, we have aligned the Sanger finger printed clone (FPC) maps from a 16-fold complexity BAC library to the QTL maps genome-wide. Fourth, we have aligned the UIUC RH maps, which are comparatively linked to human genome locations, to the pig QTL maps. Fifth, we have done a preliminary assembly of a small segment of chromosome 17 from the Sanger BAC sequences, in an effort to do the same for the entire genome. Our efforts on integrating more data types and resources into the PigQTLdb have helped to outline a genomic data integration pipeline, in which more data types and resources maybe added, such as SNP data, expression data, pathway data, and other type of data as they arise. The added tools extend the usefulness of the PigQTLdb and are steps toward an integrated animal genome information database system.