THE NCGR R-GENES DATABASE

¹ National Center for Genome Resources 1800A Old Pecos Trail Santa Fe, New Mexico 87505

² 495 Borlaug Hall University of Minnesota St. Paul, MN 55108

The National Center for Genome Resources (NCGR) R-genes database contains plant disease resistance genes and homologs assembled from various nucleotide and protein sequence databases. These sequences have been treated through a pipelined analysis designed to minimize redundancy and parse important information. These data are stored in a relational database (Sybase) with a web interface at www.ncgr.org/rgenes. Clusters of apparently redundant sequences can include such useful information as alignments of EST's to genomic sequences. Alignments of related homologs and associated inferred gene phylogenies are also viewable online. Sequences can be queried by species, motif content, or position on a phylogenetic tree. When available, map positions of genes are stored, especially for Arabidopsis sequences. Both nucleotide and corresponding putative translations are available for analysis and download.