PAG-VI: QTL CARTOGRAPHER: A SUITE OF PROGRAMS FOR MAPPING QUANTITATIVE TRAIT LOCI

PAG-VI  Plant & Animal Genome VI Conference

Town & Country Hotel, San Diego, CA, January 18-22, 1998.


C13

QTL CARTOGRAPHER: A SUITE OF PROGRAMS FOR MAPPING QUANTITATIVE TRAIT LOCI

CHRISTOPHER J. BASTEN, B. S. Weir, Zhao-Bang Zeng

    Department of Statistics, North Carolina State University, Raleigh, NC 27695-8203

QTL Cartographer is a suite of programs for mapping quantitative trait loci (QTLs) onto a genetic linkage map. The general experimental paradigm begins with a pair of inbred parental lines that differ in the trait of interest and in the set of marker genotypes. The programs use linear regression, interval mapping or composite interval mapping methods to dissect the underlying genetics of the quantitative traits. Mapping is done onto a set of linked genetic markers with known recombination frequencies. The mapping program uses a dynamic algorithm that allows a host of statistical models to be fitted and compared. The package consists of several programs written in C to perform various tasks, including simulating, reformatting or analyzing data and visualizing the results of the analyses. The mapping programs can handle data from backcrosses, intercrosses and recombinant inbreds, as well as a few other experimental designs. The source code and compiled binaries are freely available and may be obtained by through our web page (http://statgen.ncsu.edu/).


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