Plant & Animal Genome VI Conference

W25

THE UC DAVIS HORSE SYNTENY MAP

1. Veterinary Genetics Laboratory, One Shields Avenue, University of California, Davis, CA 95616-8744
2. Dept. of Animal Science, University of California, Davis, CA 95616-8744

We have placed nearly 400 markers on a synteny map, including RAPD, microsatellite and PCR-based comparative Type I markers, using a somatic cell hybrid clone panel. An additional 18 markers for blood groups, blood proteins and coat color genes have been added to the synteny map based on linkage with markers analyzed across the synteny panel. Currently we have identified 33 synteny groups, potentially corresponding to one for each chromosome of the horse karyotype. Forty-five of the markers tested across the somatic cell hybrid panel have been physically mapped thus allowing the twenty synteny groups in which those markers are placed to be assigned to chromosomes. The remaining thirteen groups are provisionally assigned to chromosomes, based on work in progress with Type I markers and consideration of the information provided by Zoo-FISH studies.