PAG-II Plant Genome II Conference

Town & Country Conference Center, San Diego, CA, January, 1994.


PG-II: MULTIPLE LOCUS RFLP DESIGNED BULK SEGREGANT ANALYSIS OF SOYBEAN CYST NEMATODE RESISTANCE QTL

MULTIPLE LOCUS RFLP DESIGNED BULK SEGREGANT ANALYSIS OF SOYBEAN CYST NEMATODE RESISTANCE QTL.

Arnaldo R. Ferreira 1, Kathy Clayton 2, David M. Webb 2, and Paul Keim 1. 1 Department of Biological Science, Northern Arizona University, Flagstaff, AZ 86011-5640. 2 Pioneer Hi-Bred Int., P.O. Box 1004, Johnston, IA 50131.


Soybean cyst nematodes (SCN) represents one of the most devastating diseases affecting soybean production. Breeding for SCN resistance is difficult and would be much more efficient if makers tightly linked to resistance genes were available for marker aided selection. RFLP markers, loosely linked to SCN resistance QTLs (Webb et al. 1994), were used to select bum from a segregating recombinant inbred population (PI437.654 X BSR-101). These bulks were fixed for resistance/susceptibility alleles using seven RFLP markers defining three genomic regions. RAPD analysis on restriction digested templates revealed 115 genetic markers differing between resistant and susceptible bulks were identified. Segregation analysis of these markers found many of these markers unreliable or were not linked to resistance QTL. However, two RAPD markers were found tightly linked to resistance QTL. Several other RAPD markers were more loosely linked to the resistance QTL. One marker resulted in the linkage between two previously unlinked RFLP markers associated with SCN resistance. Multiple-locus bulk segregant analysis using RFLP markers is a useful method for obtaining tightly linked markers where only loose marker QTL associations exist.


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