PAG-II Plant Genome II Conference

Town & Country Conference Center, San Diego, CA, January, 1994.


PG-II: DEVELOPMENT AND USE OF CHROMOSOMALLY UNBALANCED CYTOGENETIC STOCKS FOR PHYSICAL CHROMOSOME MAPPING IN COTTON (GOSSYPIUM HIRSUTUM L.)

DEVELOPMENT AND USE OF CHROMOSOMALLY UNBALANCED CYTOGENETIC STOCKS FOR PHYSICAL CHROMOSOME MAPPING IN COTTON (GOSSYPIUM HIRSUTUM L.)

Charles F. Crane, Robert Hanson, Wayne A. Raska, Don G. Czeschin, H. James Price, and David M. Stelly, Department of Soil and Crop Sciences, Texas A&M University, College Station, TX 77843.


Numerous chromosomal translocations, a number of monosomics, and a few telocentrics, have been recovered over the past 50 years in cotton after irradiation or interspecific hybridization. These rearranged or deleted chromosomes can be combined in informative ways for physical mapping of DNA probes relative to centromeres and translocation breakpoints by meiotic in situ DNA hybridization (ISH). The informative stocks have one of the following meiotic metaphase I configurations: (1) a heteromorphic telocentric bivalent), (2) a telocentric chain quadrivalent, or (3) a duplicate-deficient chain quadrivalent. The second of these types, which arises from a telocentric x translocation homozygote cross and therefore is designated TeTT, is particularly useful because each chromosomal region occupies an unambiguous position in the quadrivalent. Meiotic ISH with 18S and 5S ribosomal DNA probes to TeTT quadrivalents involving chromosomes 5, 9, and 23, has confirmed the localization of 18S and 5S sites to opposite arms of chromosome 9, and to the same arm of chromosome 23. The distribution of these ISH sites also demonstrated that the breakpoints for the TT5-9 translocation lie in the long arms of each chromosome, opposite the positions reported by Menzel based on the meiotic analysis of hybrids to other translocation homozygotes.


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