PAG-II Plant Genome II Conference

Town & Country Conference Center, San Diego, CA, January, 1994.


PG-II: CONSTRUCTION OF A COMPOSITE MAIZE MAP OF EXPRESSED SEQUENCES, BASED ON 4 INDIVIDUAL MAPS

CONSTRUCTION OF A COMPOSITE MAIZE MAP OF EXPRESSED SEQUENCES, BASED ON 4 INDIVIDUAL MAPS.

M. Causse, A. Maurice, C. Damerval, S. Santoni, D. de Vienne, Station de Genetique Vegetale, INRA, CNRS-URA 1492, UPS, Ferme du Moulon, 91190 Gif s/Yvette, France.


Candidate gene approach is a straightforward way to identify QTLs and study their function. In plant breeding, if one had the QTL itself instead of a linked marker, the efficiency of market- assisted selection would increase considerably. For this purpose, we are constructing a maize genetic map based on expressed sequences. Our map is based on the data from 4 segregating populations, one F2 And 3 recombinant inbred lines populations. In all, more than 500 individuals were genotyped. Four sources of markers were used: (i) known function genes obtained from laboratories which cloned them; (ii) polypeptides revealed by two-dimensional electrophoresis in our laboratory; (iii) sequenced cDNA for which no homology was found in gene banks, kindly provided by C. Baysdorfer (California State Univ.); (iv) anonymous probes of the maize core map (Gardiner et al, 1993, Genetics 134: 917-930). These markers were useful to integrate our map with the other maize maps. Mapping cDNA revealed some unexpected problems, among which the high rate of multicopy probes. No specific organization is deduced, excepted the duplications already mentioned. As 4 populations were used, we compared the recombination fractions among the populations. Heterogeneity was frequently observed.


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