PAG-II Plant Genome II Conference

Town & Country Conference Center, San Diego, CA, January, 1994.


PG-II: BARLEY AND MODEL QTL SYSTEMS

BARLEY AND MODEL QTL SYSTEMS

Patrick Hayes. Department of Crop and Soil Science, Oregon State University, Corvallis, OR 97331


Barley has proven to be a productive model system for public-sector genome mapping and QTL analyses. The North American Barley Genome Mapping Project has provided the technology and data required for application of these techniques to plant breeding. The intent of this presentation is to provide a overview of three projects representing distinct approaches, objectives, and targets in QTL application: (i) yield and malt extract QTL selection and validation, (ii) development of a catalog of mapped genes for resistance to barley stripe rust, and (iii) mapping the components of winterhardiness. The QTL validation project grew out of the extensive data set available in the Steptoe X Morex mapping population. Multi-environment agronomic and quality data were used to design a selection response/QTL validation study. Three tines in the original mapping population were crossed with the objective of generating two sets of progeny that would, respectively, maximize the probability of recovering an ideal genotype with all positive QTL alleles, and maximize segregation at all possible QTLS. In contrast to this 'ultimate phenotype' experiment, the barley stripe rust project is representative of exotic germplasm introgression. Barley stripe rust is simultaneously the worst possible news and the greatest opportunity. This fungal pathogen has arrived in the U.S. and virtually all barley cultivars are susceptible. Sources of genetic resistance are available but largely uncharacterized. We are proceeding to map resistance loci in various accessions and to introgress resistance loci into adapted germplasm. This will allow for the implementation of a rational disease management strategy based on judicious use of single and multiple resistance genes. Mapping the components of winterhardiness is illustrative of the power of QTL analyses to dissect complex phenotypes, validate classical epistatic models, and relate known function genes to quantitative phenotypes. We have mapped QTLs for cold tolerance, photoperiod response, and vernalization response and related these to the classical epistatic models for growth habit in barley. We have also mapped a number of induced response clones, of which the Dehydrin loci are particularly intriguing. The extensive classical and molecular genetics mapping work in barley, coupled with the ease of doubled haploid production and the economic value of this public-sector crop, make it an ideal system for testing and applying QTL theory.


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