Plant & Animal Genomes XIV Conference

January 14-18, 2006
Town & Country Convention Center
San Diego, CA

Miniaturization Of Liquid Handling Procedures In High Throughput Sequencing At The Broad Institute

David Koechlein¹ , Joe Graham² , Sheila Fisher² , Tracey Honan² , Susan Faro²

¹  Deerac Fluidics, Unit 8, Enterprise Center, Pearse Street, Dublin 2, Ireland

²  Broad Institute, 320 Charles Street, Cambridge, MA, USA

Deerac Fluidics™ Equator™ products are designed to fit a wide range of applications requiring low volume liquid handling. The products have recently been installed as part of the high throughput sequencing production process at the Broad Institute in Boston, MA, USA (formerly the Whitehead Center for Genome Research). The Genome Sequencing and Analysis program at the Broad Institute places emphasis on the development of scalable methods employing automated laboratory procedures and informatics systems. The current rate of sequencing corresponds to over 40 million lanes per year, deployed in sequencing the human, mouse, and other genomes.
This poster will describe the current process employed by Broad Institute, highlighting where the Equator™ has played a vital role in performance enhancement and cost reduction, enabling the Broad Institute to retain its position as the world’s leading genome research institute.