PAG-I Plant Genome I Conference

Town & Country Conference Center, San Diego, CA, November, 1992.


PG-I: 96pg1

MAPPING THE SOYBEAN GENOME

Randy Shoemaker 1, Kayla Polzin 1, Andrew Nickell 2 and Eberson Calvo 3, 1 USDA-ARS-FCR, 2 Department of Agronomy and 3 Department of Zoology and Genetics, Iowa State University, Ames, IA 50011.


The soybean is considered to be a "diploidized" tetraploid. We are using our molecular genetic map to characterize the structure and organization of this very complex genome. About 10-15% of the probes used in the construction of the soybean molecular genetic map detect 2 or more polymorphic loci. Occasionally, the linear order of loci on one linkage group corresponds to the linear order of duplicate loci present on a second linkage group. This suggests the evolutionary retention of some relatively large, ancient homeologous segments. Usually, however, the map position of duplicate loci appears to be random relative to the linear order of the comparable loci suggesting a great amount of genome "scrambling". We are reconstructing molecular maps using 12 independent populations and are mapping each probe with several restriction enzymes. This approach is allowing us to identify additional duplicate loci and to further resolve genome structure. Additionally we have cloned in lambda EMBL3, 7 of 9 RFLP fragments detected by probing with genomic clone pA-071, and 3 fragments detected by probing with a cDNA of sle, a soybean Lea protein. Five loci have been genetically mapped with pA-071 associated sequences and 3 sle-related loci also have been genetically mapped. Cross-hybridization among fragments indicate that the only sequences with detectable homology between all related fragments is in the immediate regions detected by pA-071 or the sle probe. Two of the 7 pA-071-related fragments and 2 of the sle-related fragments appear to be homeologous within a portion of the cloned fragments, each with a distinct break-point at which homology ends. We are also currently determining the distribution of repeated sequences along several of these fragments.


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