PAG-I Plant Genome I Conference

Town & Country Conference Center, San Diego, CA, November, 1992.


PG-I: 90pg1

COMPARISON OF RAPD MAPS FOR TWO SETS OF MAIZE RECOMBINANT-INBRED LINES.

Mitrick A. Johns, Department of Biological Sciences, Northern Illinois University, DeKalb, IL 60115.


The TXCM and COXTx recombinant-inbred maize lines (Burr et al., 1988) were analyzed by the RAPD gene-mapping technique (Williams et al., 1991) using 100 10-mer primers. A total of 290 polymorphic bands were mapped, with loci found on all chromosomes in numbers roughly proportional to the chromosome lengths. Most of the bands segregated in the expected 1:1 ratio for presence/absence, indicating that cases of two unlinked bands having similar sizes are quite rare. A band that is polymorphic in one cross is usually not polymorphic in the other cross; such a band is about equally likely to be monomorphic in the other cross as it is to be absent in both parents of the other cross. Bands of similar size (on agarose gels) in the two crosses usually map to different, unlinked locations. This results in very different genetic maps for the two crosses. At least for maize, maps based on RAPDs may not be very useful when different lines need to be compared. --RAPD primers hybridize to short inverted repeats in DNA, sequences that are also found on the ends of many plant transposable elements. A few primers generate "stray" bands, found in some progeny lines but in neither parent. These stray bands may result from genetic rearrangements in active transposable elements, but their rarity suggests that active transposable elements will not affect most RAPD mapping.


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