PAG-I Plant Genome I Conference

Town & Country Conference Center, San Diego, CA, November, 1992.


PG-I: 39pg1

ANALYSIS AND MANIPULATION OF THE TOMATO GENOME USING A HIGH DENSITY MOLECULAR LINKAGE MAP.

S.D. Tanksley, M.W. Bonierbale, P. Broun, M.W. Ganal, G.B. Martin, A.H. Paterson, J.P. Prince, and M.C. de Vicente, Department of Plant Breeding and Biometry, 252 Emerson Hall, Cornell University, Ithaca, NY 14853.


More than 1000 markers (mainly RFLPS) have been mapped onto the tomato molecular linkage map and these markers cover a total of 1276 map units. Many of these markers have also been mapped onto the potato and pepper linkage maps making it possible to determine chromosomal homeologies with a fairly high degree of precision. Several of the tomato telomeres have also been mapped using a telomere-associated tandemly repeated DNA sequence (TGRI). Thus far all of the telomeres map close to the most distal RFLP markers on the linkage map indicating that telomeres do not experience excessive rates of recombination. In contrast, areas around centromeres experience a 10 to 100-fold reduction in recombination. The tomato molecular linkage map is being used in a number of research areas including: 1) population/evolutionary studies 2) gene tagging/identification 3) map-based cloning. Highlights of results from the first two areas will be covered in this presentation.


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